Getting Rid of Inflammation w/ Specialized Pro-resolving Mediators (SPMs) – A NYC Chiropractor/Applied Kinesiologist Explains

Two weeks ago, I attended a mini-seminar from Metagenics on the use of Specialized Pro-resolving Mediators (SPMs) for the resolution of inflammation.

As you may know, inflammation is an immune response to insults such as injuries (cuts, wounds, vertebral and extremity misalignments, muscle spasms, infections (bacterial, viral or fungal) or unhealthy dietary patterns.

Although acute inflammation is a normal protective response, it can give rise to chronic inflammation if left unresolved.

Extensive research suggests that the SPMs found in OmegaGenics SPM Active (17-HDHA and 18- HEPE) may promote the body’s natural resolution of the immune response. The research has discovered that SPMs are produced at the inflamed site after the initial inflammatory response and function as “resolution agonists,” orchestrating resolution to facilitate the return to homeostasis and tissue healing. https://metagenics.com/spm-active

An important key to controlling/resolving inflammation and subsequently preventing chronic inflammatory conditions lies in SPMs and their pro-resolving properties.

SPMs are produced from long-chain polyunsaturated fatty acids – especially EPA and DHA – illustrating the importance of appropriate nutrition in the body’s resolution of inflammation.

Although EPA and DHA are metabolic precursors of SPMs, SPMs are directly responsible for resolution activities whereas EPA/DHA are involved in other beneficial biological activities.

This means that a smaller amount of SPMs can resolve inflammation better than a “ton” of EPA/DHA.

Please see the following video: Fish Oils vs SPMs: What’s the Difference?
https://vimeo.com/131679216

Anti-inflammatory drugs (NSAID’s) have been the go-to therapy for many acute and chronic inflammatory conditions. However, anti-inflammation is not the same as pro-resolution.  

To put it another way, NSAID’s shut off the fire alarm signaling inflammation while SPMs put out the fire.

In fact, NSAID’s may delay resolution activities and undermine the body’s attempt return to homeostasis and tissue healing. Unresolved inflammation and unhealed tissue can lead to fibrosis that can impair organ and muscle function.

In fact, a recent research paper review http://www.medscape.com/viewarticle/853216   Is Long-Term NSAID Use Harmful to Athletes? noted “Most recent reviews have come down on the side of restricting the use of NSAIDs, pending more information “Anti-inflammatory drugs seem to inhibit the healing process of connective tissue and the stimulating effect of exercise on connective tissue protein synthesis,” concluded the authors of a 2014 review in the journal Connective Tissue Research.

And the paper also noted, One reason for caution is that NSAIDs can cause many side effects, including kidney disease, asthma exacerbation, gastrointestinal and renal side-effects, hypertension, and other cardiovascular diseases, in addition to whatever effects they have on muscle.”

SPM Active Specialized Pro-resolving Mediators

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SPM Active is a revolutionary nutritional product developed through advanced fractionation technology featuring standardized levels of SPMs (specialized pro-resolving mediators) found in fish oil. Designed to support the body’s natural capacity to respond to physical challenges and resolve physical stress.*

Benefits:

  • A breakthrough in tissue health and immune response support*
  • Supports healthy immune cell (i.e., macrophage) resolution-related activities*

To order please go the Metagenics.com, click on Create a New Account on the top right side of the page, and use Practitioner Code DrVittoriaRepetto 20% discount on first order

For more on a integrative approach to resolving inflammation, please read https://drvittoriarepetto.wordpress.com/2015/07/18/chronic-inflammation-and-how-chiropractic-applied-kinesiology-can-help/

If you have any questions about SPMs and resolving inflammation, feel free to give me a call at 212-431-3724 or email me at drvittoriarepett@aol.com

 

 

 

© 2015-Dr. Vittoria Repetto

Want more information on Dr. Vittoria Repetto and her NYC Applied Kinesiology/Chiropractic/ NKT practice at 230 W 13th St., NYC 10011; please go to www.drvittoriarepetto.com

And please check out the Patient Testimonials page on my web site.

 Want to be in the know on holistic information and postings? 

https://www.facebook.com/wvillagechiropracticappliedkinesiologynkt/

Or join me at Twitter: www.twitter.com/DrVRepetto

 

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Nutritional Supplements: Why Metagenics ?

Metagenics is a functional medicine leader in the development of science-based products and programs that seeks to improve health by helping people achieve their genetic potential through nutrition or nutrigenomics.
Nutrigenomics is the study of the effects of foods, supplements and environmental factors have on how your genes express themselves. In other words, your genetics are not your destiny.

Helping people live happier, healthier lives by realizing their genetic potential by turning nutrigenomic discoveries into readily available natural health products.  . http://www.metagenics.com/metagenics-difference 

Lifestyle Medicine Programs for you to reclaim health. 

Breakthrough Research Establishing a higher caliber of science for better quality research and formulation 

Unsurpassed Quality: setting quality standards for the industry 

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Personal story:

For years before I became a Doctor of Chiropractic, I was concerned about the scallops around my tongue, I had learned that this may be a problem with absorption of  Vitamin B complex in my body. As I worked in a health food store, I had access to lots of different brands; some of them with mega dosages. None of the brands took away the scallops.

After chiropractic college, I attended a seminar by Metagenics and tried their Multi-Vitamin/Mineral; I took half of the recommended dosage and  in two weeks, the scallops were gone, never to return. Their formula was highly absorbable unlike previous products that I had tried.

Metagenics has opened up a new online store.

Instead of going to my website, please go to http://www.drvittoriarepetto.metagenics.com.

Please click on Create a New Account on the top right side of the page, and use Practitioner Code DrVittoriaRepetto.

The advantage of this new online store is :

20% off all first-time orders 

10% off all Recurring Orders

Free Ground Shipping on all orders (no matter how little).

And you now can use your American Express for purchases

Once you have create an account, you click on upper right hand side Log In for future purchases .

© 2015-Dr. Vittoria Repetto

Want more information on Dr. Vittoria Repetto and her NYC Applied Kinesiology/Chiropractic/ NKT practice at 230 W 13th St., NYC 10011; please go to www.drvittoriarepetto.com

And please check out the Patient Testimonials page on my web site.

 Want to be in the know on holistic information and postings? 

https://www.facebook.com/wvillagechiropracticappliedkinesiologynkt/

Or join me at Twitter: www.twitter.com/DrVRepetto

 

A NYC Chiropractor Recommends How to Do A Healthy Liver Detox.

A NYC Chiropractor Recommends How to Do A Healthy Liver Detox.

I have this big old liver spot on my left hand, it’s on Large Intestine point 4 and I’ve had it since I was 28 yrs old (I’m 60 now) and it is the result of a badly constructed “liver detox”

The liver detox was one involving drinking only apple juice and doing enemas for 3 days and we are still seeing this type of cleanse or detox in various reincarnations and they all involve depriving oneself of nutrients which does a lot more hurt than good.

Let me explain: the liver is the major way that our bodies remove toxins like heavy metals, industrial compounds and pollutants that can be associated w/ fatigue, muscle pain and weakness, cancer, headaches, nerve degeneration, headaches, rashes, loss of memory, etc.

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The liver does this in two Phases; Phase 1 involves oxidation and Phase 2 involves conjugation.

Oxidation involves using oxygen and enzymes to turn a toxin (most toxins are fat-soluble) into a water-soluble substance so they can be more easily executed by the liver or kidneys. Foods that can help Phase 1 do its job are cruciferous vegetables like broccoli and kale, oranges, caraway seeds; nutrients that help are Vitamin C  & E , zinc, selenium and cooper  Milk thistle and members of the thistle family like artichokes help the Phase 1 process.

However the product of this Phase 1 can be even more toxic so the liver needs to process the Phase 1 via a Phase 2 process called conjugation. Conjugation involves combining the oxidized compounds w/ sulfur, amino acids (building block of protein) and organic acids  and  methylation  via Vitamin B12, choline & folic acid and generation of glutathione via N-acetylcysteine so  toxic products can be executed in the bile which then leaves the body via the large intestine.

Phase 2 is helped by adequate protein  as found in nuts, seeds, beans, meat, fish , eggs and dairy, alliums  as found in garlic, onions, citrus, cruciferous vegetables, bioflavonoids as found in peppers, celery, carrots oregano, rosemary, olive oil, pomegranates, and cruciferous vegetables.

Medium chain triglycerides, mono-unsaturated fats, Vitamin B1, B2, niacin, B5 and magnesium help with the energy production needed to perform these tasks

And of course, the body needs to have adequate fiber in order to move these toxins out of the body quickly before they are reabsorbed.

So you can see that water or juice fasts are harmful to the body as they deplete the body of the nutrients need for a healthy detoxification.

I now do  a “spring cleaning –liver detox” week in which only foods that are organic /glass fed, etc are eaten  and I add a liver support program that has all the Phase 1 and Phase nutrients (from Metagenics  https://drvittoriarepetto.metagenics.com/ultraclear that my liver needs  for detoxification.

For patients who have altered detoxification function may be due to genetic predisposition, a history of chronic nutrient insufficiency, and/or toxin overload, which can result in a build-up of stored toxins and a subsequent increase in symptoms and/or tissue damage, I recommend: https://drvittoriarepetto.metagenics.com/ultraclear-plus

 

And I know that I (or my patients) will not be getting any more big old liver spots from a badly constructed liver detox.

 © 2011-Dr. Vittoria Repetto

 To order please go the Metagenics.com, click on Create a New Account on the top right side of the page, and use Practitioner Code DrVittoriaRepetto
20% discount on first order
10% discount on recurring orders

 Want more information on Dr. Vittoria Repetto and her NYC Applied Kinesiology/Chiropractic/ NKT practice at 230 W 13th St., NYC 10011; please go to www.drvittoriarepetto.com

And please check out the Patient Testimonials page on my web site.

 Want to be in the know on holistic information and postings? 

https://www.facebook.com/wvillagechiropracticappliedkinesiologynkt/

Or join me at Twitter: www.twitter.com/DrVRepetto

 

Your Genetics Are Not Your Destiny!

As many of you may know I use Metagenics nutritional products in my office; Metagenics is a functional medicine leader in the development of science-based products and programs that seeks to improve health by helping people achieve their genetic potential through nutrition or nutrigenomics.
Nutrigenomics is the study of the effects of foods, supplements and environmental factors have on how your genes express themselves. In other words, your genetics are not your destiny.
 
This week in the quarterly magazine NY Spirit, an article from Annemarie Colbin, health educator and founder of The Natural Gourmet Institute for Health and Culinary Arts in NYC wrote an article on how the genes work and the affect of food on them.
 
Enjoy!

Are you utilizing your folic acid? The case for metabolically active form of folic acid – L-5-MTHF

Roughly one-third of the general population may have a genetic variation that impairs their ability to properly utilize folic acid.

L-5-methyltetrahydrofolate (L-5-MTHF) is the metabolically active form of folic acid. The folic acid found in food has to be cleaved (digested) from protein carriers in order to be absorbed. This process is inefficient in some individuals. Once absorbed, dietary (and supplemental) folic acid has to then undergo several biochemical conversions in the body to become L-5-MTHF. Roughly one in three Americans have genetically inefficient enzymes that help create L-5-MTHF. By supplementing with L-5-MTHF, one can be assured of getting the benefits of folic acid, regardless of their ability to absorb or convert it to the active form. If you are an individual with impaired ability to utilize regular folic acid, L-5-MTHF supplementation can make a truly dramatic difference in your health.

L-5-MTHF plays a role in DNA synthesis and repair. Inadequate levels of 5-MTHF is linked to childhood leukemia. Cancers of the colon and breast are also associated with suboptimal L-5-MTHF status, as is the precancerous condition called cervical dysplasia. In a study involving smokers, high doses of folic acid and vitamin B12 reversed precancerous cellular changes in the lungs.

Folic acid’s importance to human health has to do in part with its role in a biochemical process called methylation. Methylation refers to the transfer of methyl groups (one carbon bound to three hydrogen atoms). Methylation occurs billions of times in the body each day and is essential for health.

L-5-MTHF is very important to genetic expression. Methyl groups are strategically placed on certain genes to inactivate them. Every cell in the human body has the genetic information to produce every other type of cell. The thing is that most of the genes are not active. Methyl groups (supplied indirectly by L-5-MTHF) silence the genes that should not be active in a given cell at a given time. This is obviously critical for good health. Some of the genes within our cells are tumor promoters. Proper methylation, which requires L-5-MTHF, keeps these genes silenced. The importance of L-5-MTHF involves more than its role in promoting proper genetic expression, DNA synthesis and repair.

L-5-MTHF also plays a role in dopamine and serotonin metabolism.

L-5-MTHF also plays an important role L-5-MTHF also plays an important role in detoxication of a variety of compounds, including environmental toxins (such as mercury, lead, arsenic and tin), medications, and some of the body’s own hormones. Estrogens are detoxified through methylation. Inadequate levels of L-5-MTHF cause potentially toxic build-up of estrogens in the body, which increases risk to breast, prostate and other cancers. Other conditions of estrogen excess, such as uterine fibroids and endometriosis, are also more likely to occur and be more severe. Histamine, epinephrine (adrenaline), and norepinephrine are also detoxified by methylation. Inadequate L-5-MTHF could therefore potentially worsen allergy and stress-related symptoms.

L-5-MTHF is critical for the detoxication of homocysteine. Conditions associated with elevated homocysteine levels include coronary artery disease, heart attack, stroke, deep vein thrombosis, peripheral vascular disease, miscarriage, birth defects, depression, sensorineural hearing loss, osteoporosis, cancer, arthritis, dementia, Alzheimer’s disease, Parkinson’s disease, and complications of diabetes. Do you know what your homocysteine level is?

© 2009-Dr. Vittoria Repetto

Please check out Metagenics for products w/L-5-MTHF at http://www.metagenics.com

Click on Create an Account and use Practitioner Code – DrVittoriaRepetto

Thanks

Want more information on Dr. Vittoria Repetto and her NYC Applied Kinesiology/Chiropractic/ NKT practice at 230 W 13th St., NYC 10011; please go to www.drvittoriarepetto.com

And please check out the Patient Testimonials page on my web site.

 Want to be in the know on holistic information and postings? 

https://www.facebook.com/wvillagechiropracticappliedkinesiologynkt/

Or join me at Twitter: www.twitter.com/DrVRepetto